DELETION OF A PATHOGENIC MUTATION-CONTAINING EXON OF COL7A1 ALLOWS CLONAL GENE EDITING CORRECTION OF RDEB PATIENT EPIDERMAL STEM CELLS

Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells

Recessive dystrophic epidermolysis bullosa is a severe skin fragility disease caused by loss of functional type VII AEG FEB52600ZM 60cm Semi Integrated Dishwasher collagen at the dermal-epidermal junction.A frameshift mutation in exon 80 of COL7A1 gene, c.6527insC, is highly prevalent in the Spanish patient population.We have implemented gene-editi

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